Volume 4 No. 2, April 2009

The Color Doppler Study on the Superior Mesenteric Artery and Femoral Artery in Cirrhotic Patients

Abeer S. Ghobashy, Faten M. Salem, Mahmoud Dawoud & Mohammed El-Refaey

Radiodiagnosis & Imaging Department, Faculty of Medicine Tanta University, Egypt
Tanta Med. Sc. J 2009; 4(2):186-192

Abstract provided by Publisher   
 

Aim: is to demonstrate the changes in the Doppler ultrasonography of splanchnic (superior mesenteric artery) and extra-splanchnic circulation (Femoral artery) in patients with cirrhosis. Patient & Methods: The study was conducted on 20 cases as control and 56 patients, classified according to Child-Paugh (n.65) grading into 3 groups. The age of the patients ranged from 39 to 52 years, all cases were subjected to history taking clinical examination, complete liver functions tests, abdominal ultrasonography, and Doppler study for superior mesenteric and femoral arteries. Data from the Doppler study were analyzed to calculate the mean blood flow and the pulsatility index of the superior mesenteric and femoral arteries in different groups. Results: The results show a significantly higher superior mesenteric artery blood flow in each Child group than in control group. In addition, the superior mesenteric artery pulsatility index was significantly lower in each Child group than in control group. The study gives evidence, through superior mesenteric artery pulsatility index, that the primary site of the arterial vasodilatation in human cirrhosis occurs in splanchnic arterial circulation. Regarding femoral artery as an extra-splanchnic sample, the study shows a significant increase in the blood flow in grade B patients, with significantly lower pulsatility index in the same sample, the pulsatility index of femoral artery was also significantly lower in grade A patients than in control group. Conclusion: Doppler study has an important role to understand the vascular hemodynamics in the patients with cirrhosis; it is also valuable to recognize the degree of liver dysfunction. As many drugs are used in cases of cirrhosis with portal hypertension like B-blockers which affect the splanchnic hemodynamics, Doppler study and follow up is useful to minitor the response to treatment and to adjust the dose of medication. Finally this study depicts the role of extrasplancine arterial circulation in arterial pressure haemostatic response in the patients with severs cirrhosis.

ICID 897174