|
Color Doppler
Sonography, In Acute Viral Hepatitis In Children
Hanaa A El-Araby1 , Enas Korayem1 & Naglaa
Dabees2
Pediatrics & Radiology Departments, National Liver Institute,
Menoufiya University1 & Radiology department, Tanta
Univrsity Hospital2.
Tanta Med. Sc. J 2008; 3(2):55-65
Article type: Original article
Aim: The aim was to study the pattern of hemodynamic changes in both
portal vein (PV) and hepatic artery (HA) through the different
stages of acute viral hepatitis in children and to determine any
sonographic correlation with the prognosis. Patients & Methods:
Color Doppler US were performed on 50 patients with acute viral
hepatitis (AVH) for four consecutive weeks and compared the results
with those obtained on 20 normal controls. Results: The portal vein
diameter and velocity showed no significant changes neither during
different stages of acute hepatitis nor with the control group,
while during the acute phase, the peak-systolic velocity (PSV) and
end-diastolic velocity (EDV) of the hepatic artery were
significantly higher than those in normal arteries (P<0.01). During
the recovery phase, these indices of the hepatic artery decreased
significantly to the control levels (P<0.01). The resistive index
(RI) related to vascular resistance in the hepatic artery during the
acute phase were significantly less than those in normal arteries
(P<0.01), and they increased significantly to the control levels
during the recovery phase (P<0.01). Conclusion: Doppler sonography
is useful for imaging hepatic hemodynamic changes in children with
acute viral hepatitis. We found that significant changes occur only
in hepatic artery while no changes occurred in the portal vein. Also
measurements of hepatic arterial flow during acute phase may be
reliable for determining the prognosis of patients with viral
hepatitis where the increased hepatic arterial blood flow during the
acute phase may provide a marker for earlier recovery from
hepatitis-induced damage and may be considered as a good marker for
the prognosis. |