Volume 3 No. 3, July 2008

Treatment of Appendiceal Masses: What Is the Best Approach?
Mohamed  Altabakh, Ashraf  Elattar, Hamdy  Elnashartawy, Tamer  Abd Elhafez

Department of General Surgery, Faculty of Medicine, Tanta University, Egypt.
Tanta Med. Sc. J 2008; 3(3):96-100
Article type: Original article

Background/Aim: For appendiceal masses, various treatment options are available. Commonly, the mass is treated conservatively followed by interval appendectomy, six weeks later. Other surgeons prefer immediate appendectomy following resolution of the mass. Less commonly, the mass may be treated only conservatively, without the need for appendectomy. No randomized trials have been reported in the literature to point the best option out. We conducted a prospective, randomized clinical trial to compare these three commonly used options. PATIENTS & METHODS: Over a three-years period (from June 1998 to May 2001), 60 patients with appendiceal masses were randomly allocated to one of three groups: Group A; patients in this group received initial conservative therapy, followed by interval appendectomy six weeks later, Group B; patients in this group received initial conservative therapy followed, as soon as the appendiceal mass resolved, by appendectomy during the same admission (early appendectomy). Group C; patients in this group received conservative therapy only. Short-term outcome measures included: operative time, operative difficulty, occurrence of operative and postoperative complications, and the length of hospital stay. The following long-term outcome measures were looked at: number of follow up visits, presence of severe wound pain, scar appearance, and recurrence of appendicitis in group C patients. RESULTS: The presence of intra-abdominal adhesions and the need to extent the wound, and thus elongating the operative time, were significantly higher in group B in comparison with group A. In all, six patients in group B had postoperative complications against none in group A (p<0.05). Mean duration of hospital stay was significantly shorter in group C. Group C patients had significantly less follow up visits in comparison with the other two groups (p<0.05). Five patients in group A and eight patients in group B complained of severe wound-related pain (P>0.05). Two patients in group A and five in group B expressed concern about the ugliness of the appendectomy scar (p>0.05). Only 2 of the 20 patients in group C developed recurrent acute appendicitis. CONCLUSIONS: In patients with appendiceal masses, although interval appendectomy seems to be a safer and more cost-effective approach, when compared to early appendectomy, the conservative only approach promises even better results. The small study size and the relatively short duration of follow up in our study made it difficult to draw strict conclusions in favor of the last approach.

ICID 871176