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The Level of Brain
Natriuretic Peptide in Patients with Mitral Stenosis before and
After Percutaneous Balloon Mitral Valvuloplasty
Mohmaed Abdalaal1 & Mohamed Attia2
Departments of
cardiology1, clinical pathology2, Faculty of
Medicine, Tanta University, Egypt.
Tanta Med. Sc. J 2007; 2(3):54-60
Article type: Original article
Aim: the aim is to assess the plasma level of
brain natriuretic peptide before and after percutaneous balloon
mitral valvuloplasty in patients with mitral stenosis. Patients and
methods: the brain natriuretic peptide level was measured in 20
patients with rheumatic mitral stenosis and in another 20 age- and
gender- matched healthy subjects as a control group. Patients with
mitral stenosis underwent percutaneous balloon mitral valvuloplasty.
Plasma brain natriuretic peptide level was measured before and after
the procedure. Results: the level of brain natriuretic peptide was
found to be higher in patients with mitral stenosis {239.5 pg/ml}
compared to the control group (15 pg/ml). The level of brain
natriuretic peptide was found to be reduced from 239.5 pg/ml to
162.75 pg/ml after percutaneous balloon mitral valvuloplasty.
Conclusion: the level of brain natriuretic peptide was found to be
reduced in patients with mitral stenosis after percutaneous balloon
mitral valvuloplasty. This reduction was found to be correlated with
the reduction in pulmonary artery systolic pressure (r=0.7) and the
increase in the mitral valve area (r=0.55).
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