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Prevalence of Carotid
and Renal Artery Stenosis in Patients with Significant Coronary
Artery Disease
Raghda Ghonimy, Ehab Elgendy, Amr Badr, Suzan Bayomi, Mohamed
Elseteha, Hatem Elsokkary & Ayman Elsaied.
Cardiology department,
Faculty of Medicine, Tanta University, Egypt.
Tanta Med. Sc. J 2007; 2(3):109-119
Article type: Original article
Background/Aim: Atherosclerosis as a vascular
disease can involve any artery in the body including large and
medium sized arteries. Only a few angiographic studies have
correlated the presence and severity of coronary artery disease with
atherosclerosis in other arteries. The aim of this study is to
evaluate the prevalence of the carotid and renal artery stenosis in
patients with documented coronary artery disease and the role of
predisposing risk factors for such affection in Egyptian patients.
Patients & Methods: This study included 100 patients with documented
significant coronary artery disease. All were subjected to carotid
and renal angiography. They were divided into: group I which
included patients with significant carotid artery stenosis (>50%)
either unilateral or bilateral, and group II which included patients
with normal carotid. They divided again into: group A which included
patients with significant renal artery stenosis (>50%), while group
B included patients with normal renal angiography. For all patients,
random blood sugar, serum urea, creatinine and complete lipid
profile was assessed. Results: Group I included 17 patients while
Group II included 83 patients with documented significant coronary
artery disease. There were significant correlations between either
of age, hypertension, dyslipedemia, diabetes mellitus and presence
of carotid artery stenosis. While there was no relation between
carotid artery stenosis with neither gender nor smoking. Number of
the affected coronary arteries was the significant multivariate
predictor of significant carotid artery stenosis. While group A
included 7 patients and group B included 93 patients with documented
coronary artery disease. Hypertension and serum levels of both urea
and creatinine were significantly univariate predictor of the
presence of renal artery stenosis. The significant multivariate
predictor of presence of renal artery stenosis was serum level of
blood urea. Conclusion: The prevalence of significant carotid artery
stenosis with significant coronary artery disease was found to be
17%. The prevalence of significant renal artery stenosis with
significant coronary artery disease was found to be 7%. Carotid
artery disease is more common in patients with old age,
hypertension, dyslipidemia and with more than two vessel diseased
coronaries. Renal artery disease is more common in hypertensive
patients with elevated blood urea and serum creatinine levels and
with more than two vessel diseased coronaries.
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